发明名称 Purification of taxanes
摘要 Disclosed is a method of crystallizing a taxane comprising combining the taxane and methylene chloride to obtain a solution and adding an anti-solvent to the solution to obtain a crystalline taxane, wherein the anti-solvent is selected from the group consisting of hexane and heptane.
申请公布号 US8703982(B2) 申请公布日期 2014.04.22
申请号 US20100705247 申请日期 2010.02.12
申请人 BUCHER BRIAN A.;DESIMONE, III EDWARD M.;FRANKE ROLAND R.;GALLAGHER REX T.;HAND BARRY J.;HOWE CHRISTOPHER D.;JOHNSON JAMES A.;JUCHUM JOHN S.;PLANTE MARC A.;SAMBANDAM T. G.;YANG DONG S.;PHYTON HOLDINGS LLC 发明人 BUCHER BRIAN A.;DESIMONE, III EDWARD M.;FRANKE ROLAND R.;GALLAGHER REX T.;HAND BARRY J.;HOWE CHRISTOPHER D.;JOHNSON JAMES A.;JUCHUM JOHN S.;PLANTE MARC A.;SAMBANDAM T. G.;YANG DONG S.
分类号 C07D305/00;C07D407/00 主分类号 C07D305/00
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