发明名称 |
Cancer cell-specific apoptosis-inducing agents that target chromosome stabilization-associated genes |
摘要 |
The present inventors discovered that inhibition of the expression of various genes associated with chromosome stabilization induces cancer cell-specific apoptosis and inhibits cell proliferation. Compounds that inhibit expression of a gene associated with chromosome stabilization or inhibit the function of a protein encoded by such a gene are thought to have cancer cell-specific apoptosis-inducing effects. |
申请公布号 |
US8703930(B2) |
申请公布日期 |
2014.04.22 |
申请号 |
US201313900380 |
申请日期 |
2013.05.22 |
申请人 |
GENECARE RESEARCH INSTITUTE CO., LTD. |
发明人 |
TAKAGI MOTOKI;FUTAMI KAZUNOBU;SHIMAMOTO AKIRA;FURUICHI YASUHIRO |
分类号 |
C07H21/02;A61K31/7105;A61K31/7115;A61K38/00;A61K39/395;A61K45/00;A61P35/00;C12N15/00;C12N15/11;C12Q1/68;G01N33/15;G01N33/50;G01N33/574 |
主分类号 |
C07H21/02 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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