摘要 |
Methods and devices for use in detecting the iodine status of a subject are provided. The methods and devices utilize an iodide binding protein (IBP) to specifically bind to and facilitate detection of iodide in a saliva sample from a subject. The detected iodide can be used to detect the iodide status of the subject. In several examples, the IBP includes an iodide binding domain from a vanadium dependent iodoperoxidase (vIPO), including a catalytically inactive vIPO. |