发明名称 Increased molecule capture rate into a nanopore
摘要 A mechanism for capturing molecules is provided. A nanopore through a membrane separates a first chamber from a second chamber, and the nanopore, the first chamber, and the second chamber are filled with ionic buffer. A narrowed neck is at a middle area of the first chamber, and the narrowed neck is aligned to an entrance of the nanopore. The narrowed neck has a high intensity electric field compared to other areas of the first chamber having low intensity electric fields. The narrowed neck having the high intensity electric field concentrates the molecules at the middle area aligned to the entrance of the nanopore. Voltage applied between the first chamber and the second chamber drives the molecules, concentrated at the entrance of the nanopore, through the nanopore.
申请公布号 US8702940(B2) 申请公布日期 2014.04.22
申请号 US201213570600 申请日期 2012.08.09
申请人 PENG HONGBO;STOLOVITZKY GUSTAVO A.;WANG DEQIANG;INTERNATIONAL BUSINESS MACHINES CORPORATION 发明人 PENG HONGBO;STOLOVITZKY GUSTAVO A.;WANG DEQIANG
分类号 G01N27/447;B82Y35/00;G01N27/453 主分类号 G01N27/447
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