| 摘要 |
An isolated peptide comprising a Huntingtin (Htt) amino acid sequence being no longer than 15 amino acids, wherein said Htt amino acid sequence comprises the sequence X X 2 X 3 X 4 X, wherein X is a hydrophobic amino acid or threonine, X 2 is a hydrophobic amino acid, X 3 is a hydrophobic amino acid, X 4 is an acidic amino acid and X is selected from the group consisting of glycine, serine and alanine, the peptide capable of specifically inhibiting the activity of caspase 6. |
