发明名称 |
METHODS OF MANUFACTURING TOPICAL COMPOSITIONS AND APPARATUS FOR THE SAME |
摘要 |
Provided according to some embodiments of the invention are methods of manufacturing a pharmaceutical composition. In some embodiments, such methods include homogenizing at a first excipient composition that includes a viscosity agent and at least one solvent to form a first premix composition; separately homogenizing at least one active pharmaceutical ingredient (API) and a second excipient composition to form a second premix composition; and combining the first premix composition and the second premix composition to form the composition. The pre-mixing of constituents may increase the stability of the API and provide uniformity of the dispersion of the constituents throughout the final topical composition. |
申请公布号 |
US2014107071(A1) |
申请公布日期 |
2014.04.17 |
申请号 |
US201314133973 |
申请日期 |
2013.12.19 |
申请人 |
NOVAN, INC. |
发明人 |
KOUGOULOS ELEFTHERIOS;STASKO NATHAN |
分类号 |
A61K31/655;A61K47/34;B01F7/00;B01F15/02;B01F15/06 |
主分类号 |
A61K31/655 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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