METHOD OF COATING AND ENCAPSULATION OF CELLS AND CELL AGGREGATES WITH THICK AND STABLE POLYMER MEMBRANE

摘要

The present invention relates to a cross-linked polymer for surface modification of a cell or cell aggregate, said cross-linked polymer comprising micelles of a maleimide-conjugated amphiphilic first polymer, and a second polymer having multiple thiol groups. It further relates to cell and cell aggregates encapsulated by such polymers, and theire use in therapy, as well as kits and methods for preparing such polymers.