IONIZATION DEVICE, MASS SPECTROMETER INCLUDING THE IONIZATION DEVICE, OR IMAGE GENERATION SYSTEM INCLUDING THE MASS SPECTROMETER

摘要

PROBLEM TO BE SOLVED: To provide an ionization device achieving high ionization efficiency by causing a substance that does not easily dissolve in a solvent in an atmospheric pressure environment to actively dissolve in the solvent.SOLUTION: An ionization device includes: a laser light irradiation unit 6 irradiating at least a region of a surface of a sample with laser light to desorb a particle from the sample; a liquid holding unit having an end portion and capable of holding a liquid on an outer periphery of the end portion; an ion extraction electrode 7 extracting an ionized ion; and a voltage application means applying a voltage between the liquid and the extraction electrode to desorb the ion from the liquid held on the outer periphery of the end portion. The ionization device has at least two operation modes including a first operation mode in which the liquid at the end portion is brought into contact with the surface of the sample and then an ionized particle is released from the end portion, and a second operation mode in which the liquid at the end portion is disposed at a location separated from the surface of the sample and the particle desorbed from the surface of the sample as a result of being irradiated with the laser light is ionized using the liquid at the end portion.