| 发明名称 |
METHODS AND MEANS FOR TREATMENT OF OSTEOARTHRITIS |
| 摘要 |
The present invention relates to in vivo and in vitro methods, agents and compound screening assays for inducing anabolic stimulation of chondrocytes, including cartilage formation enhancing pharmaceutical compositions, and the use thereof in treating and/or preventing a disease involving a systemic or local decrease in mean cartilage thickness in a subject. |
| 申请公布号 |
US2014107181(A1) |
申请公布日期 |
2014.04.17 |
| 申请号 |
US201314055955 |
申请日期 |
2013.10.17 |
| 申请人 |
GALAPAGOS N.V. |
发明人 |
VANDEGHINSTE NICK;TOMME PETER HERWIG MARIA;MICHIELS FRITS;MA LIBIN;MILLE-BAKER BLANDINE;VAN ES HELMUTH H.G. |
| 分类号 |
C07H21/04;A61K38/17;C12N15/11;C12Q1/68;G01N33/50;G01N33/68 |
主分类号 |
C07H21/04 |
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