<p>An orthotopic artificial bladder endoprosthesis comprises a collapsible casing (2) constituted by a multi-layered silicone membrane having an external surface (2b) and an internal surface (2a) both coated with pyrolytic turbostratic carbon, two tubular connection elements (5) fixed to the casing (2) and connectable to ureters of a patient and a connector (3) fixed to the casing (2) connectable to the urethra of the patient; a coating (6) made of a PGA fiber fabric associated at least with said casing ( 2 ).</p>