发明名称 HYDROGEL PRODRUGS
摘要 The present invention relates to a process for the preparation of a hydrogel and to a hydrogel obtainable by said process. The present invention further relates to a process for the preparation of a hydrogel-spacer conjugate, to a hydrogel-spacer conjugate obtainable by said process, to a process for the preparation of a carrier-linked prodrug and to carrier- linked prodrugs obtainable by said process, in particular to carrier- linked prodrugs that provide for a controlled or sustained release of a drug from a carrier. In addition, the invention relates to the use of the hydrogel for the preparation of a carrier-linked prodrug.
申请公布号 WO2014056926(A1) 申请公布日期 2014.04.17
申请号 WO2013EP70962 申请日期 2013.10.08
申请人 ASCENDIS PHARMA A/S 发明人 RAU, HARALD;VOIGT, TOBIAS;LAUFER, BURKHARDT;BISEK, NICOLA;HAHN, FRANZISKA;KNAPPE, THOMAS
分类号 C08J3/24;A61K47/10;A61K47/48;C08F2/32;C08G65/32;C08G65/332;C08G83/00;C08J3/075 主分类号 C08J3/24
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