发明名称 TYROSINE KINASE INHIBITORS
摘要 The present disclosure provides compounds and pharmaceutically acceptable salts that are tyrosine kinase inhibitors, in particular BLK, BMX, EGFR, HER2, HER4, ITK, JAK3, TEC, BTK, and TXK and are therefore useful for the treatment of diseases treatable by inhibition of tyrosine kinases such as cancer and inflammatory diseases such as arthritis, and the like. Also provided are pharmaceutical compositions containing such compounds and pharmaceutically acceptable salts and processes for preparing such compounds and pharmaceutically acceptable salts.
申请公布号 US2014107151(A1) 申请公布日期 2014.04.17
申请号 US201214117870 申请日期 2012.05.16
申请人 PRINCIPAL BIOPHARMA INC.;PRINCIPIA BIOPHAMA INC. 发明人 GOLDSTEIN DAVID MICHAEL;BRAMELD KENNETH ALBERT
分类号 C07D471/04;A61K31/437;A61K31/4439;A61K31/444;A61K31/454;A61K31/4545;A61K45/06;C07D401/12 主分类号 C07D471/04
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