发明名称 MAMMALIAN CELL CULTURE PROCESSES FOR PROTEIN PRODUCTION
摘要 The present invention describes methods and processes for the production of proteins by animal cell or mammalian cell culture. In one aspect, the methods comprise the growth of cells in a growth factor/protein/peptide free medium. In another aspect, the methods comprise the addition of growth factors during the production phase. The methods sustain a high viability of the cultured cells, and can yield an increased end titer of protein product, and a high quality of protein product.
申请公布号 US2014106405(A1) 申请公布日期 2014.04.17
申请号 US201314052987 申请日期 2013.10.14
申请人 BRISTOL-MYERS SQUIBB COMPANY 发明人 TIAN JUN;BORYS MICHAEL;LI ZHENGJIAN;ABUABSI NICHOLAS;AU ANGELA;QIAN NAN-XIN;DAI XIAO-PING
分类号 C07K14/705 主分类号 C07K14/705
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