| 摘要 |
The invention provides methods of identifying biomarkers associated with autism or autism spectrum disorder based upon quantitative trait association analyses using genome-wide genotype data combined with ease-control association analyses using distinct ASD phenotypes identified on the basis of symptomatic profiles, including deficits in language usage, non-verbal communication, social development, play skills, and insistence on sameness and rituals. Also provided are compositions identified using the methods of the invention and use thereof. |
