发明名称 |
METHOD TO DETERMINE THE ABSORPTION COEFFICIENT IN TURBID MEDIA |
摘要 |
The invention relates to a method to determine the wavelength dependent absorption coefficient of a turbid medium using overlapping illumination-detection areas comprising the steps of a) retrieving a calibration spectrum (CA) from a reference measurement using a reference sample; b) carrying out a measurement on an actual sample for determining the absolute reflection spectrum (Rabs) using a raw spectrum measured on the sample (Smedium) and the calibration spectrum (CΛ); C) using the absolute reflection spectrum (Rabs) for determining the wavelength dependent absorption coefficient by minimizing the difference between the measured absolute reflection spectrum (Rabs) and a model function (Rabsmodel). wherein the model function (Rabsmodel) is modelled using a predetermined equation based on prior knowledge of the combination of a dependence of the effective photon path length (LPF) on a scattering phase function (PF); a dependence of the absolute reflectance in the absence of absorption (Rabs0) on scattering phase function (PF). The invention further relates to a system and a computer program product for determining the wavelength dependent absorption coefficient of a turbid medium. |
申请公布号 |
US2014107951(A1) |
申请公布日期 |
2014.04.17 |
申请号 |
US201214006643 |
申请日期 |
2012.03.26 |
申请人 |
STERENBORG HENRICUS JOSEPHUS CORNELUS MARIA;KANICK STEPHEN CHAD;AMELINK ARJEN;ROBINSON DOMINIC JAMES;ERASMUS UNIVERSITY MEDICAL CENTER ROTTERDAM |
发明人 |
STERENBORG HENRICUS JOSEPHUS CORNELUS MARIA;KANICK STEPHEN CHAD;AMELINK ARJEN;ROBINSON DOMINIC JAMES |
分类号 |
G01N33/26 |
主分类号 |
G01N33/26 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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