USE OF 3-HYDROXY-3-METHYLGLUTARYL COENZYME A REDUCTASE INHIBITORS FOR THE MANUFACTURE OF A MEDICAMENT FOR THE TREATMENT OF DIABETIC NEUROPATHY

摘要

PROBLEM TO BE SOLVED: To provide a pharmaceutical composition suitable for treating diabetic neuropathy, in particular, for improving nerve conduction velocity or nerve blood flow.SOLUTION: Provided is a pharmaceutical composition for treating diabetic neuropathy using a statin drug. Preferably, the statin drug is selected from pravastatin, simvastatin, cerivastatin, fluvastatin, atorvastatin and (E)-7-[4-(4-fluorophenyl)-6-isopropyl-2-[methyl(methylsulfonyl)amino]pyrimidin-5-yl](3R,5S)-3,5-dihydroxyhept-6-enoic acid or a pharmaceutically acceptable salt thereof. Preferably, the statin drug is used in combination with at least one other drug used for treating diabetes or the complications of diabetes.