发明名称 |
hnRNP A2* PROTEIN, NUCLEIC ACID FOR CODING PROTEIN AND USE THEREOF |
摘要 |
The present invention provides an hnRNP A2* protein, nucleic acid for coding the protein and a use thereof. The protein contains a protein, a protein segment or a protein analog or derivative having an amino acid sequence shown as SEQ ID NO.1. The hnRNP A2* protein can actively unloosen telomere G-quadruplexes, bind the minimum binding site at the 3' tail end of telomere, expose five nucleotide tails which can be matched with a telomere enzyme RNA template and promote the extension of telomere under the effect of telomere enzyme, thereby maintaining the cell division potential. |
申请公布号 |
WO2014056422(A1) |
申请公布日期 |
2014.04.17 |
申请号 |
WO2013CN84838 |
申请日期 |
2013.10.08 |
申请人 |
INSTITUTE OF ZOOLOGY, CHINESE ACADEMY OF SCIENCES |
发明人 |
TAN, ZHENG;ZHAO, YONG;WANG, FENG;HAO, YUHUA |
分类号 |
C07K14/47;A61K38/17;A61P35/00;A61P43/00;C12N15/12 |
主分类号 |
C07K14/47 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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