摘要 |
A kind of multiply modified derivatives of gelatin having not only the structure of formula (I) but also one of structures of formula (II), (III), and (IV) as well. In the formulas, G refers to gelatin residue comprising A type, B type and the type of gene restructuring; R1 refers to alkylene, or a linkage group with amide; R2 refers to alkyl, or aryl; R3 refers to alkylene; R4 refers to carboxyl or carboxylate. The multiple modifying ways of gelatin comprise the modifying way of hydrophobic activating the amide of branch amine group of gelatin, the modifying way of carboxylating the amide of branch amine group of gelatin, the modifying way of thiolating the branch carboxyl group of gelatin, and the modifying way of thiolating the modified product of carboxylating the amide of branch amine group of gelatin. The multiply modified derivatives of gelatin have versatile chemical structures and multi-functions. The multiply modified derivatives of gelatin linked with crosslinking agent can provide crosslinked gelatin material. The crosslinked gelatin material can be used for matrix of bacterial growth. |