| 发明名称 |
HALOGEN-ALKYL-1,3 OXAZINES AS BACE1 AND/OR BACE2 INHIBITORS |
| 摘要 |
<p>The present invention provides compounds of formula (I) having BACE1 and/or BACE2 inhibitory activity, their manufacture, pharmaceutical compositions containing them and their use as therapeutically active substances. The active compounds of the present invention are useful in the therapeutic and/or prophylactic treatment of e.g. Alzheimer's disease and type 2 diabetes.</p> |
| 申请公布号 |
EP2718286(A1) |
申请公布日期 |
2014.04.16 |
| 申请号 |
EP20120725743 |
申请日期 |
2012.06.04 |
| 申请人 |
F.HOFFMANN-LA ROCHE AG;SIENA BIOTECH S.P.A. |
发明人 |
WOLTERING, THOMAS |
| 分类号 |
C07D413/12;A61K31/5355;A61P25/28 |
主分类号 |
C07D413/12 |
| 代理机构 |
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