发明名称 BETA-AND GAMMA-AMINO-ISOQUINOLINE AMIDE COMPOUNDS AND SUBSTITUTED BENZAMIDE COMPOUNDS
摘要 Disclosed are beta and gamma-amino isoquinoline amide compounds and substituted benzamide compounds. In particular, the invention provides compounds that affect the function of kinases in a cell and that are useful as therapeutic agents or with therapeutic agents. The compounds of the invention are useful in the treatment of a variety of diseases and conditions including eye diseases such as glaucoma, cardiovascular diseases, and diseases characterized by abnormal growth, such as cancers. The invention further provides compositions containing the beta or gamma-amino isoquinoline amide compounds or substituted benzamide compounds.
申请公布号 EP2326623(B1) 申请公布日期 2014.04.16
申请号 EP20090790775 申请日期 2009.07.23
申请人 AERIE PHARMACEUTICALS, INC. 发明人 DELONG, MITCHELL, A.;STURDIVANT, JILL, MARIE;ROYALTY, SUSAN, M.
分类号 C07D217/02;A61K31/472;A61P27/06;C07D217/24;C07D333/24;C07D401/12;C07D405/12;C07D409/12;C07D413/12;C07D417/12 主分类号 C07D217/02
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