发明名称 |
SYSTEMS AND METHODS FOR ELECTRONIC DETECTION WITH NANOFETS |
摘要 |
There is disclosed a system for electrical charge detection comprising a nanoFET device. Also disclosed is a method of electrical charge detection for single molecule sequencing. The method includes attaching a macromolecule or assemblies thereof to a gate of a nanoFET device and flowing in a solution of charge tags, where a charge tag includes a nucleotide attached to a charge complex. The method also includes incorporating one charge tag into the macromolecule or assemblies thereof and cleaving the charge tags from the macromolecule or assemblies thereof. The method further includes detecting at least one of current and voltage from the nanoFET device. |
申请公布号 |
EP2165353(A4) |
申请公布日期 |
2014.04.16 |
申请号 |
EP20080796064 |
申请日期 |
2008.06.30 |
申请人 |
APPLIED BIOSYSTEMS INC. |
发明人 |
OLDHAM, MARK, F.;NORDMAN, ERIC, S. |
分类号 |
G01N27/414;C12Q1/68;G01N33/543 |
主分类号 |
G01N27/414 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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