发明名称 |
TRIAZOLONE COMPOUNDS AS mPGES-1 INHIBITORS |
摘要 |
The present disclosure is directed to compounds of formula (I), and pharmaceutically acceptable salts thereof, as mPGES-1 inhibitors. These compounds are inhibitors of the microsomal prostaglandin E synthase-1 (mPGES-1) enzyme and are therefore useful in the treatment of pain and/or inflammation from a variety of diseases or conditions, such as asthma, osteoarthritis, rheumatoid arthritis, acute or chronic pain and neurodegenerative diseases. |
申请公布号 |
EP2718284(A1) |
申请公布日期 |
2014.04.16 |
申请号 |
EP20130745477 |
申请日期 |
2013.06.10 |
申请人 |
GLENMARK PHARMACEUTICALS S.A. |
发明人 |
GHARAT, LAXMIKANT ATMARAM;MUTHUKAMAN, NAGARAJAN;KHAIRATKAR-JOSHI, NEELIMA;KATTIGE, VIDYA GANAPATI |
分类号 |
C07D403/12;A61K31/4196;A61P29/00;C07D249/12;C07D401/04;C07D401/10;C07D403/04;C07D403/10;C07D405/12;C07D409/14;C07D413/10;C07D417/10;C07D417/12 |
主分类号 |
C07D403/12 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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