发明名称 |
YKL-40 as a general marker for non-specific disease |
摘要 |
The present invention relates to methods of diagnosing the presence of a non-specific disease or disorder in a subject, wherein a determined level of YKL-40 above a reference level indicates the presence of a non-specific disease or disorder. The subject may suffer from a variety of diseases or disorders. The reference level may be a reference level obtained from healthy individuals or it may be a previous measurement obtained from the same subject. The present invention furthermore relates to a method for classifying the severity of a non-specific disease or disorder in a subject, wherein a determined level of YKL-40 above or below one or more reference levels gives the severity of said non-specific disease or disorder. The present invention further relates to a kit and a device that may be used in the method of the present invention comprising means for measuring the level of YKL-40 in a sample; and means for comparing the measured level of YKL-40 with at least one reference level of YKL-40. |
申请公布号 |
US8697384(B2) |
申请公布日期 |
2014.04.15 |
申请号 |
US20090812409 |
申请日期 |
2009.01.22 |
申请人 |
JOHANSEN JULIA;BOJESEN STIG;NORDESTGAARD BØRGE GRØNNE;NIELSEN HANS JØRGEN;CHRISTENSEN IB JARLE;HERLEV HOSPITAL;HVIDOVRE HOSPITAL;RIGSHOSPITALET |
发明人 |
JOHANSEN JULIA;BOJESEN STIG;NORDESTGAARD BØRGE GRØNNE;NIELSEN HANS JØRGEN;CHRISTENSEN IB JARLE |
分类号 |
C12Q1/37 |
主分类号 |
C12Q1/37 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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