发明名称 |
VIABLE NON-TOXIC GRAM NEGATIVE BACTERIA |
摘要 |
The present invention provides non-toxic Gram-negative bacteria. In particular, the present invention provides viable Gram-negative bacteria (e.g., E. coli) substantially lacking lipopolysaccharide (LPS, endotoxin) within the outer membrane. The present invention further provides methods of generating viable non-toxic Gram-negative bacteria and uses thereof. The present invention also provides compositions and methods for inducing immune responses and for researching and developing therapeutic agents. |
申请公布号 |
CA2637903(C) |
申请公布日期 |
2014.04.15 |
申请号 |
CA20072637903 |
申请日期 |
2007.01.19 |
申请人 |
THE REGENTS OF THE UNIVERSITY OF MICHIGAN |
发明人 |
WOODARD, RONALD WESLEY;MEREDITH, TIMOTHY CHARLES;AGGARWAL, PARAG |
分类号 |
A61K39/00;C08B37/00;C12N1/21 |
主分类号 |
A61K39/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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