发明名称 |
HUMANE ANTISTOFFER MOD HEPATITIS C-VIRUS (HCV) OG ANVENDELSER DERAF |
摘要 |
<p>Isolated human monoclonal antibodies which bind to hepatitis C virus (HCV), and related antibody-based compositions and molecules, are disclosed. The human antibodies can be produced in a transfectoma or in a non-human transgenic animal, e.g., a transgenic mouse, capable of producing multiple isotypes of human monoclonal antibodies by undergoing V-D-J recombination and isotype switching. Also disclosed are pharmaceutical compositions comprising the human antibodies, non-human transgenic animals, and hybridomas which produce the human antibodies, and therapeutic and diagnostic methods for using the human antibodies.</p> |
申请公布号 |
DK2125889(T3) |
申请公布日期 |
2014.04.14 |
申请号 |
DK20080725537T |
申请日期 |
2008.02.13 |
申请人 |
UNIVERSITY OF MASSACHUSETTS |
发明人 |
SLOAN, SUSAN;BABCOCK, GREGORY, J.;BROERING, TERESA;AMBROSINO, DONNA;THOMAS, WILLIAM D., JR. |
分类号 |
C07K16/10;A61K39/00;A61K39/395;A61P31/14 |
主分类号 |
C07K16/10 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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