发明名称 TETRAHYDROQUINOLINE DERIVATIVES AND THEIR USE AS EPAC INHIBITORS
摘要 The invention relates to tetrahydroquinoline derivatives and their use in the treatment and/or the prevention of a disease wherein the Epac protein is involved, such as inflammation, cancer, vascular diseases, kidney diseases, cognitive disorders and cardiac diseases.
申请公布号 WO2014053315(A1) 申请公布日期 2014.04.10
申请号 WO2013EP69298 申请日期 2013.09.17
申请人 INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM);UNIVERSITE PAUL SABATIER TOULOUSE III;UNIVERSITÉ PARIS-SUD;UNIVERSITE D'ORLEANS 发明人 FISCHMEISTER, RODOLPHE;BISSERIER, MALIK;BOUYSSOU, PASCAL;LEZOUALC'H, FRANK;BLONDEAU, JEAN-PAUL;COURILLEAU, DELPHINE
分类号 A61K31/435;A61P9/02;C07D215/08 主分类号 A61K31/435
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