发明名称 TREATMENT OF PROGRESSIVE NEURODEGENERATIVE DISEASE WITH IBUDILAST
摘要 PROBLEM TO BE SOLVED: To provide methods for treating or preventing progressive neurodegenerative diseases, and their associated symptoms.SOLUTION: Ibudilast of the following formula (3-isobutyryl-2-isopropylpyrazolo[1,5-a]pyridine) which has been widely used in Japan for relieving symptoms associated with ischemic stroke or bronchial asthma or its pharmaceutically acceptable salt, are administered for progressive neurodegenerative diseases, at a daily dosage amount ranging from 30 mg to 240 mg, or from 30 mg to 180 mg, 60 mg to 120 mg, or 20 mg to 80 mg, once to three times daily.
申请公布号 JP2014062118(A) 申请公布日期 2014.04.10
申请号 JP20130255214 申请日期 2013.12.10
申请人 MEDICINOVA INC 发明人 KALAFER MICHAEL E;LOCKE KENNETH W;MATSUDA KAZUKO;GAMMANS RICHARD E
分类号 A61K31/437;A61P25/00 主分类号 A61K31/437
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