| 摘要 |
FIELD: medicine, pharmaceutics.SUBSTANCE: invention refers to molecular biology and pharmacology. What is presented is a method for the prediction of the pharmaceutical effectiveness of adalimumab for treating rheumatoid arthritis, wherein the method involves measuring a level of at least one of ADAMTS4 iRNA and ADAMTS5 iRNA in a sample taken from a subject, and determining if adalimumab is effective for rheumatoid arthritis in a subject on the basis of a level of at least one of ADAMTS4 iRNA and ADAMTS5 iRNA considered as a value.EFFECT: method may be used in medicine in treating rheumatoid arthritis.3 cl, 2 dwg, 8 tbl |
