发明名称 |
THE WATER-INSOLUBLE DOCETAXCEL COVERED WITH AMORPHOUS SURFACTANT AND METHOD FOR PREPARING THE SAME |
摘要 |
The present invention relates to a water-insoluble docetaxcel and a method for manufacturing the same. The water-insoluble docetaxcel according to an embodiment of the present invention includes 100 parts by weight of a docetaxcel and 10 to 200 parts by weight of a surfactant having two or more alkyl chains attached to a hydrophilic portion the for docetaxcel. The surfactant is bonded by amorphously surrounding the outside of the docetaxcel and is dissolved in water in a type of oil painting, wherein an average diameter of the surfactant attached docetaxcel is 0.5-30 micrometers and an average range of a size is within±200% relative to the diameter. [Reference numerals] (AA) Slightly soluble material; (BB) Hydrophilic part of a surfactant; (CC) Surfactant; (DD) Alkyl chain part of the surfactant |
申请公布号 |
KR20140043573(A) |
申请公布日期 |
2014.04.10 |
申请号 |
KR20120106087 |
申请日期 |
2012.09.24 |
申请人 |
KOLMAR KOREA |
发明人 |
KWEON, DON SUN;YOU, WOO YOUNG |
分类号 |
A61K9/08;A61K9/107;A61K31/337;C07D305/14 |
主分类号 |
A61K9/08 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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