发明名称 THE WATER-INSOLUBLE DOCETAXCEL COVERED WITH AMORPHOUS SURFACTANT AND METHOD FOR PREPARING THE SAME
摘要 The present invention relates to a water-insoluble docetaxcel and a method for manufacturing the same. The water-insoluble docetaxcel according to an embodiment of the present invention includes 100 parts by weight of a docetaxcel and 10 to 200 parts by weight of a surfactant having two or more alkyl chains attached to a hydrophilic portion the for docetaxcel. The surfactant is bonded by amorphously surrounding the outside of the docetaxcel and is dissolved in water in a type of oil painting, wherein an average diameter of the surfactant attached docetaxcel is 0.5-30 micrometers and an average range of a size is within±200% relative to the diameter. [Reference numerals] (AA) Slightly soluble material; (BB) Hydrophilic part of a surfactant; (CC) Surfactant; (DD) Alkyl chain part of the surfactant
申请公布号 KR20140043573(A) 申请公布日期 2014.04.10
申请号 KR20120106087 申请日期 2012.09.24
申请人 KOLMAR KOREA 发明人 KWEON, DON SUN;YOU, WOO YOUNG
分类号 A61K9/08;A61K9/107;A61K31/337;C07D305/14 主分类号 A61K9/08
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