METHOD FOR CONTROLLED MEXIDOL-INDUCED PLATELET AGGREGATION DECREASE IN EXPERIMENT

摘要

FIELD: medicine, pharmaceutics.SUBSTANCE: invention refers to medicine, particularly to experimental pharmacology, and concerns methods for controlled platelet aggregation decrease in vitro. That is ensured by administering mexidol to plasma containing 200-220 thousand/mcl of platelets immediately after plasma sampling. Mexidol is used in the concentration of 0.1 to 0.8 mg/ml of an incubation mixture. The incubation is conducted for 10-15 minutes at room temperature.EFFECT: method provides platelet aggregation to a desired value.