发明名称 |
CRYSTALLINE, ANHYDROUS FORMS OF OXYMORPHONE HYDROCHLORIDE |
摘要 |
Crystalline, anhydrous hydrochloride salts of 4,5α-epoxy-3,14-dihydroxy-17-methylmorphinan-6-one (oxymorphone) are disclosed and three polymorphic forms of these salts are reported. The invention further relates to a method for the production of such salts, a pharmaceutical composition comprising an effective amount of such a salt and such a salt as a medicament and for the treatment and/or prevention of pain. |
申请公布号 |
EP2714695(A1) |
申请公布日期 |
2014.04.09 |
申请号 |
EP20120723666 |
申请日期 |
2012.05.24 |
申请人 |
GRUENENTHAL GMBH |
发明人 |
FISCHER, ANDREAS;PETERS-GROTH, DAGMAR;LISCHKE, DAGMAR |
分类号 |
C07D489/08 |
主分类号 |
C07D489/08 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|