发明名称 TWO TYPES OF CRYSTALLINE OF PINOCEMBRIN: A AND B, THEIR PREPARATION AND THEIR USE FOR MANUFACTURE OF PHARMACEUTICAL COMPOSITIONS
摘要 Two crystalline forms of pinocembrin of formula (I): ± and ², their preparation and their use for manufacture of pharmaceutical compositions. There exists difference between them in bioavailability. They are used for treating and preventing cerebral ischemic diseases by protective action of neurovascular unit, and enhancing blood drug level in vivo.
申请公布号 EP2360152(B1) 申请公布日期 2014.04.09
申请号 EP20080878072 申请日期 2008.11.13
申请人 CSPC ZHONGQI PHARMACEUTICAL TECHNOLOGY (SHIJIAZHUANG) CO., LTD.;INSTITUTE OF MATARIA MEDICA, CHINESE ACADEMY OF MEDICAL SCIENCES 发明人 DU, GUANHUA;LV, YANG;WU, SONG;WANG, KE;CHANG, YING;YANG, ZHIHONG;TONG, YUANFENG;GAO, MEI
分类号 C07D311/22;A61K31/353;A61P9/10;C07D311/32 主分类号 C07D311/22
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