发明名称 RADIOACTIVE IODINE LABELED COMPOUND HAVING AFFINITY FOR AMYLOID
摘要 It is intended to provide a compound that is effective as a diagnostic imaging probe that targets amyloid, and a diagnostic agent for Alzheimer's disease comprising the compound. Provided are a compound represented by the following formula (1), or salt thereof: wherein R 1 is a radioactive halogen substituent, A 1 and A 2 independently represent CH or N, and a diagnostic agent for Alzheimer's disease, comprising the compound represented by the above formula or a salt thereof. The above compound and the above diagnostic agent for Alzheimer's disease transfer into brain after administration, and indicate good accumulation on amyloid deposited in the brain.
申请公布号 EP2716641(A1) 申请公布日期 2014.04.09
申请号 EP20120789191 申请日期 2012.05.18
申请人 NIHON MEDI-PHYSICS CO., LTD. 发明人 OKUMURA, YUKI;MAYA, YOSHIFUMI;SHOYAMA, YOSHINARI;ONISHI, TAKAKO
分类号 C07D471/04;A61K31/437;A61K51/00;A61K51/04;C07F7/22 主分类号 C07D471/04
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