发明名称 |
Monoclonal antibodies binding to avian influenza virus subtype H5 haemagglutinin and uses thereof |
摘要 |
The present invention provides monoclonal antibodies that bind specifically to H5 subtype avian influenza virus hemagglutinin (HA) proteins, and can block the binding activity of at least 50% of the known monoclonal antibodies to the H5 subtype avian influenza virus hemagglutinin (HA) protein. The monoclonal antibodies can be used for the detection, diagnosis, prevention, and treatment of avian influenza viruses, especially the H5 subtype of avian influenza viruses. The present invention also provides the related hybridoma cell lines, isolated nucleic acid molecules and short peptides, as well as medical composition and medical diagnostic equipment and kit containing the monoclonal antibody. |
申请公布号 |
EP2716656(A1) |
申请公布日期 |
2014.04.09 |
申请号 |
EP20130166514 |
申请日期 |
2008.06.16 |
申请人 |
XIAMEN UNIVERSITY;BEIJING WANTAI BIOLOGICAL PHARMACY ENTERPRISE CO., LTD. |
发明人 |
CHEN, YIXIN;LUO, WENXIN;ZHANG, JUN;XIA, NINGSHAO;GUAN, YI;CHEN, HONGLIN |
分类号 |
C07K16/18;A61K38/08;A61K38/10;A61K39/395;A61P31/16;C07K7/06;C07K7/08;C07K14/11;C07K16/10;C07K16/46;C12N5/12;C12N15/13;C12N15/63;G01N33/53;G01N33/569 |
主分类号 |
C07K16/18 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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