发明名称 |
NON-PEPTIDYL POLYMER-INSULIN MULTIMER AND METHOD FOR PRODUCING THE SAME |
摘要 |
<p>The present invention relates to a non-peptidyl polymer-insulin multimer comprising two or more of a non-peptidyl polymer-insulin conjugate prepared by linking a non-peptidyl polymer and insulin via a covalent bond, in which the conjugates are complexed with cobalt ion to form a multimer, a method and kit for the preparation of the multimer, a pharmaceutical composition for the prevention or treatment of diabetes comprising the multimer as an active ingredient, and a method for preventing or treating diabetes by administering the composition to a subject.</p> |
申请公布号 |
EP2714095(A2) |
申请公布日期 |
2014.04.09 |
申请号 |
EP20120792533 |
申请日期 |
2012.06.01 |
申请人 |
HANMI SCIENCE CO., LTD. |
发明人 |
LIM, SUNG IN;JANG, MYUNG HYUN;KIM, DAE JIN;JUNG, SUNG YOUB;KWON, SE CHANG |
分类号 |
A61K47/48;A61K38/28;A61K47/30;A61P3/10 |
主分类号 |
A61K47/48 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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