发明名称 |
Controlled-release melatonin compositions and related methods |
摘要 |
This disclosure relates to controlled-release melatonin compositions and related methods. In one embodiment, a controlled-release medicament composition comprises melatonin dispersed in a controlled melatonin release portion comprising a polymer matrix, the polymer matrix adapted to encapsulate the melatonin in a melatonin solubility enhancing pH environment and to maintain the melatonin solubility enhancing pH environment when the composition is located in a melatonin solubility diminishing pH environment for allowing an effective amount of melatonin to be released into the melatonin solubility diminishing pH environment. |
申请公布号 |
US8691275(B2) |
申请公布日期 |
2014.04.08 |
申请号 |
US201213359638 |
申请日期 |
2012.01.27 |
申请人 |
SHAH SYED M.;HASSAN DANIEL;ZX PHARMA, LLC |
发明人 |
SHAH SYED M.;HASSAN DANIEL |
分类号 |
A61K9/14;A61K31/4045;A61P5/00 |
主分类号 |
A61K9/14 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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