发明名称 Method for processing microbiologically produced cyclic oligopeptides
摘要 The present invention relates to a method for processing microbiologically produced, non-polar, cyclic oligopeptides comprising the step of a) extracting the entire fermentation broth incident to the microbiological production process using a liquid extractant that contains ether and is immiscible with water, wherein the amount of extractant is sufficient to form a two-phase system together with the total fermentation broth, and novel solvates of cyclosporin A and methyl-t-butyl ether.
申请公布号 US8691770(B2) 申请公布日期 2014.04.08
申请号 US200913055715 申请日期 2009.07.29
申请人 BERTEL STEPHAN;SANDOZ AG 发明人 BERTEL STEPHAN
分类号 A61K38/13;A61K38/12;C07K1/14;C07K5/00;C07K7/00;C07K7/64;C07K16/00;C07K17/00 主分类号 A61K38/13
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