| 发明名称 |
Pyrazole derivatives as protein kinase modulators |
| 摘要 |
The invention provides compounds of the formula (I) having protein kinase B inhibiting activity: Also provided are pharmaceutical compositions containing the compounds, methods for preparing the compounds and their use as anticancer agents. |
| 申请公布号 |
US8691806(B2) |
申请公布日期 |
2014.04.08 |
| 申请号 |
US201213536174 |
申请日期 |
2012.06.28 |
| 申请人 |
BERDINI VALERIO;SAXTY GORDON;VERDONK MARINUS LEENDERT;WOODHEAD STEVEN JOHN;WYATT PAUL GRAHAM;BOYLE ROBERT GEORGE;SORE HANNAH FIONA;WALKER DAVID WINTER;COLLINS IAN;DOWNHAM ROBERT;CARR ROBIN ARTHUR ELLIS;ASTEX THERAPEUTICS LIMITED;THE INSTITUTE OF CANCER RESEARCH: ROYAL CANCER HOSPITAL;CANCER RESEARCH TECHNOLOGY LIMITED |
发明人 |
BERDINI VALERIO;SAXTY GORDON;VERDONK MARINUS LEENDERT;WOODHEAD STEVEN JOHN;WYATT PAUL GRAHAM;BOYLE ROBERT GEORGE;SORE HANNAH FIONA;WALKER DAVID WINTER;COLLINS IAN;DOWNHAM ROBERT;CARR ROBIN ARTHUR ELLIS |
| 分类号 |
A61K31/397;A61K31/415;C07D231/12;C07D401/10;C07D413/10 |
主分类号 |
A61K31/397 |
| 代理机构 |
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