发明名称 |
Ensayos de actividad de endopeptidasa re-dirigida basados en inmunología |
摘要 |
The present specification discloses SNAP-25 immune response inducing compositions, methods of making a- SNAP-25 antibodies that selectively binds to an epitope comprising a SNAP-25 having a carboxyl-terminus at the PI residue of the BoNT/A cleavage site scissile bond, ±-SNAP-25 antibodies that selectively bind to an epitope comprising a SNAP-25 having a carboxyl-terminus at the P1 residue of the BoNT/A cleavage site scissile bond, methods of detecting retargeted endopeptidase activity, and methods of detecting neutralizing ±-re-targeted endopeptidase antibodies. |
申请公布号 |
ES2440597(T9) |
申请公布日期 |
2014.04.07 |
申请号 |
ES20100709360T |
申请日期 |
2010.03.12 |
申请人 |
ALLERGAN, INC. |
发明人 |
WANG, JOANNE;ZHU, HONG;HODGES, D. DIANE;FERNANDEZ-SALAS, ESTER |
分类号 |
G01N33/50;C12Q1/37 |
主分类号 |
G01N33/50 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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