METHOD FOR PREDICTION OF CHROMATIC 3D STRUCTURE BASED ON A PRIMARY DNA SEQUENCE

摘要

The present invention relates to a method for estimating a DNA three dimensional structure by estimating the distribution of nucleosomes with histone protein transformation in a random DNA sequence using DNA sequence specificity related to the histone protein transformation of the nucleosomes. The method for estimating the DNA three dimensional structure comprises: a step of obtaining the DNA sequence specificity of the nucleosomes related to the histone protein transformation; and a step of estimating the distribution of the nucleosomes with histone protein transformation in a random DNA sequence. [Reference numerals] (100) Obtaining DNA sequence specificity related to the histone protein transformation; (300) Estimating the distribution of the nucleosomes with histone protein transformation in a random DNA sequence; (AA) Start; (BB) End