发明名称 |
1,3-OXAZINES AS BACE1 AND/OR BACE2 INHIBITORS |
摘要 |
The present invention provides compounds of formula I having BACE1 and/or BACE2 inhibitory activity, their manufacture, pharmaceutical compositions containing them and their use as therapeutically active substances. The active compounds of the present invention are useful in the therapeutic and/or prophylactic treatment of e.g. Alzheimer's disease and type 2 diabetes. |
申请公布号 |
KR20140041538(A) |
申请公布日期 |
2014.04.04 |
申请号 |
KR20137032852 |
申请日期 |
2012.05.11 |
申请人 |
F. HOFFMANN-LA ROCHE AG;SIENA BIOTECH S.P.A. |
发明人 |
HILPERT HANS;NARQUIZIAN ROBERT;PINARD EMMANUEL;POLARA ALESSANDRA;ROGERS EVANS MARK;WOLTERING THOMAS;WOSTL WOLFGANG |
分类号 |
C07D413/10;A61K31/5355;A61P25/28;C07D265/08 |
主分类号 |
C07D413/10 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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