发明名称 |
LIPOSOME COMPRISING ELASTIN-LIKE POLYPEPTIDE CONJUGATED TO A MOIETY CONTAINING A HYDROPHOBIC GROUP, CHEMOSENSITIZER AND ANTICANCER AGENT AND USE THEREOF |
摘要 |
The present invention relates to a liposome comprising an elastin-like polypeptide (ELP) conjugated to a moiety containing a hydrophobic group, a chemosensitizer, and an anticancer agent, wherein the ELP conjugated to moiety containing the hydrophobic group is filled in a lipid bilayer. The present invention provides a pharmaceutical composition including the liposome and a method for delivering the chemosensitizer and the anticancer agent to a target site of a subject by using the liposome. [Reference numerals] (AA) Cell viability(%); (BB) Free doxorubicin; (CC) Glass doxorubicin |
申请公布号 |
KR20140041304(A) |
申请公布日期 |
2014.04.04 |
申请号 |
KR20120116852 |
申请日期 |
2012.10.19 |
申请人 |
SAMSUNG ELECTRONICS CO., LTD. |
发明人 |
PARK, SUN MIN;KIM, HYUN RYOUNG;PARK, JAE CHAN;KIM, MIN SANG;CHAE, SU YOUNG |
分类号 |
A61K9/127;A61K47/48 |
主分类号 |
A61K9/127 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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