ASSEMBLY FOR NUCLEIC ACID SEQUENCING BY MEANS OF TUNNEL CURRENT ANALYSIS

摘要

The invention relates to an assembly for nucleic acid sequencing by means of tunnel current analysis, comprising at least two electrically conductive particles having a diameter from 1 nm to 100 nm and at least two electrically insulating particles having a diameter from 1 nm to 100 nm, wherein the particles are in particular spherically shaped. The assembly also comprises at least two first electrodes for contacting the electrically conductive particles and a substrate on which the first electrodes and the particles are arranged. The four particles are arranged substantially in a planar square. The conductive particles lie diagonally opposite each other, and the insulating particles lie diagonally opposite each other. The gap between the four particles is used as a solid-state nanopore for nucleic acid sequencing.