发明名称 |
DIMERIC MOLECULAR COMPLEXES WITH FREE CYSTEINE RESIDUES AND CONJUGATES THEREOF |
摘要 |
<p>The invention relates generally to dimeric molecular complexes comprising two fusion proteins. Each fusion protein comprises a biological effector moiety, a polypeptide spacer sequence, and an IgE CH4 dimerization domain. The dimeric molecular complexes may be conjugated, at a defined site, to other molecules including drug moieties, cytotoxic agents, labels (such as detectable labels), or biocompatible polymers.</p> |
申请公布号 |
WO2012078761(A3) |
申请公布日期 |
2014.04.03 |
申请号 |
WO2011US63748 |
申请日期 |
2011.12.07 |
申请人 |
BAYER HEALTHCARE LLC;LIGHT, DAVID;SZYMANSKI, PAUL;SETO, MARIAN;CORNELIUS, ALINE |
发明人 |
LIGHT, DAVID;SZYMANSKI, PAUL;SETO, MARIAN;CORNELIUS, ALINE |
分类号 |
C07K16/00;A61K39/00 |
主分类号 |
C07K16/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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