发明名称 HETEROCYCLIC COMPOUNDS AND THEIR USES
摘要 PROBLEM TO BE SOLVED: To provide selective inhibitor compounds of phosphatidylinositol 3-kinase (PI3K) activity.SOLUTION: Provided are compounds represented by the specified formula or pharmaceutically acceptable salts of the compounds, where Xand Xare each a C or N atom; Y is N, O or S; Z is C or N; n is 0, 1, 2 or 3; Ris a specific monocycle; Rto Rare each independently halo, haloalkyl or the like.
申请公布号 JP2014058526(A) 申请公布日期 2014.04.03
申请号 JP20130218925 申请日期 2013.10.22
申请人 AMGEN 发明人 CHEN YI;TIMOTHY D CUSHING;JASON A DUQUETTE;GONZALES LOPEZ DE TURISO FELIX;HAO XIAOLIN;HE XIAO;BRIAN LUCAS;MACGEE LAWRENCE R;ANDREAS REICHELT;RZASA ROBERT M;JENNIFER SEGANISH;YOUNGSOOK SHIN;ZHANG DAWEI
分类号 C07D487/04;A61K31/519;A61P7/02;A61P9/00;A61P9/10;A61P9/12;A61P17/06;A61P19/02;A61P29/00;A61P35/00;A61P35/02;A61P37/06;A61P43/00;C12N15/113 主分类号 C07D487/04
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