发明名称 |
PURIFICATION OF HETERO-DIMERIC IMMUNOGLOBULINS |
摘要 |
The present invention describes novel hetero-dimeric immunoglobulinvariants or fragments thereof, which have reduced or eliminated binding to Protein A, Protein G or both Protein A and Protein G. Also encompassed in the present invention are methods for the selective purification of hetero-dimeric immunoglobulins or fragments thereof using Protein A and Protein G. |
申请公布号 |
WO2014049003(A1) |
申请公布日期 |
2014.04.03 |
申请号 |
WO2013EP69989 |
申请日期 |
2013.09.25 |
申请人 |
GLENMARK PHARMACEUTICALS S.A. |
发明人 |
BLEIN, STANISLAS;COMPER, FABRIZIO;OLLIER, ROMAIN;WASSMANN, PAUL |
分类号 |
C07K16/46;B01D15/38 |
主分类号 |
C07K16/46 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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