摘要 |
The present invention relates to compounds for use as therapeutic agents, particularly in the treatment and/or prevention of proliferative disorders, such as cancer, especially brain cancers/tumours, wherein the compounds are generally defined by the formula I: wherein A is an aryl or heteroaryl ring system; and R1 to R 4 are various possible substituent groups, provided that at least one of an R2 group, the R3 group, or an R4 group is or comprises a hydroxy, amino, NH(R x ), or mercapto group. |