发明名称 |
SYNTHESIS OF CARBAMOYLPYRIDONE HIV INTEGRASE INHIBITORS AND INTERMEDIATES |
摘要 |
A synthesis approach providing an early ring attachment via a bromination to compound I-I yielding compound II-II: whereby a final product such as AA: can be synthesized. In particular, the 2,4-difluorophenyl-containing sidechain is attached before creation of the additional ring Q. |
申请公布号 |
US2014094605(A1) |
申请公布日期 |
2014.04.03 |
申请号 |
US201314096191 |
申请日期 |
2013.12.04 |
申请人 |
VIIV HEALTHCARE COMPANY;SHIONOGI & CO., LTD. |
发明人 |
YOSHIDA HIROSHI;TAODA YOSHIYUKI;JOHNS BRIAN ALVIN;KAWASUJI TAKASHI;NAGAMATSU DAIKI |
分类号 |
C07D471/22 |
主分类号 |
C07D471/22 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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