发明名称 |
LIPID COATED NANOPARTICLES CONTAINING AGENTS HAVING LOW AQUEOUS AND LIPID SOLUBILITIES AND METHODS THEREOF |
摘要 |
Provided herein are compositions that include delivery system complexes comprising a nano-precipitated bioactive compound, wherein the nano-precipitate is encapsulated by a liposome or has at least a portion of its surface coated with a liposome. Because the liposomes contain nano-precipitates of bioactive compounds, the liposomes are capable of utilization in formulating essentially insoluble forms of bioactive agents. Also provided herein are methods for the treatment of a disease or an unwanted condition in a subject, wherein the methods comprise administering the delivery system complexes. |
申请公布号 |
CA2925687(A1) |
申请公布日期 |
2014.04.03 |
申请号 |
CA20132925687 |
申请日期 |
2013.09.26 |
申请人 |
THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL |
发明人 |
GUO, SHUTAO;HUANG, LEAF;RAMISHETTI, SRINIVAS |
分类号 |
A61K9/127;A61K9/16;A61K47/30;A61K47/48 |
主分类号 |
A61K9/127 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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