| 摘要 |
PROBLEM TO BE SOLVED: To provide a combination of an anti-malignant tumor agent containing HKI-272 and vinorelbine.SOLUTION: The present invention copes with the need in the art by providing a regimen, a composition and a method using a HKI-272 compound and a vinorelbine compound in order to treat a cancer such as a solid tumor and a metastatic breast cancer. One aspect provides a regimen for treatment of a neoplasm in a subject, where the regimen comprises a step of administering a vinorelbine compound and a step of administering a HKI-272 compound. Desirably, the vinorelbine compound is vinorelbine and the HKI-272 compound is HKI-272. In one embodiment, the neoplasm is a breast cancer. |
